Publications

2018

Di Pietro V, Yakoub KM, Scarpa U, Di Pietro C, Belli A. MicroRNA Signature of Traumatic Brain Injury: From the Biomarker Discovery to the Point-of-Care. Front Neurol. 2018 Jun 14;9:429. doi: 10.3389/fneur.2018.00429. eCollection 2018.

Davies DJ, Clancy M, Dehghani H, Lucas SJE, Forcione M, Yakoub KM, Belli A. Cerebral oxygenation in traumatic brain injury; Can a non-invasive frequency domain near-infrared spectroscopy device detect changes in brain tissue oxygen tension as well as the established invasive monitor?  J Neurotrauma. 2018 Oct 19. doi: 10.1089/neu.2018.5667. [Epub ahead of print]

Yakoub KM, O’Halloran P, Davies DJ, Bentley C, Watson CN, Forcione M et al. Study of Concussion in Rugby Union through MicroRNAs (SCRUM): a study protocol of a prospective, observational cohort study. BMJ Open 2018;8:e024245. doi:10.1136/bmjopen-2018-024245

Sullivan J, Mirbahai L, Lord JM. Major trauma and acceleration of the ageing process. Ageing Res Rev. 2018 Dec;48:32-39. doi: 10.1016/j.arr.2018.10.001. Epub 2018 Oct 11.

Di Pietro V, Porto E, Ragusa M, Barbagallo C, Davies D, Forcione M et al. Salivary MicroRNAs: Diagnostic Markers of Mild Traumatic Brain Injury in Contact-Sport. Front Mol Neurosci. 2018 Aug 20;11:290. doi: 10.3389/fnmol.2018.00290. eCollection 2018.

Begum G, O’Neill J, Chaudhary R, Blachford K, Snead DRJ, Berry M et al. Altered Decorin Biology in Proliferative Vitreoretinopathy: A Mechanistic and Cohort Study. Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):4929-4936. doi: 10.1167/iovs.18-24299

Kuravi SJ, Harrison P, Rainger GE, Nash GB. Ability of Platelet-Derived Extracellular Vesicles to Promote Neutrophil-Endothelial Cell Interactions. Inflammation. 2018 Sep 14. doi: 10.1007/s10753-018-0893-5. [Epub ahead of print]

McCarthy EM, Floyd H, Addison O, Zhang ZJ , Oppenheimer PG, Grover LM. Influence of Cobalt Ions on Collagen Gel Formation and Their Interaction with Osteoblasts. ACS Omega.2018;3(8):10129–10138. DOI: 10.1021/acsomega.8b01048. Publication Date (Web): August 30, 2018

Duggal NA, Snelson C, Shaheen U, Pearce V, Lord JM. Innate and adaptive immune dysregulation in critically ill ICU patients. Sci Rep. 2018 Jul 5;8(1):10186. doi: 10.1038/s41598-018-28409-7.

Hutchings SD, Naumann DN, Hopkins P, Mellis C, Riozzi P, Sartini S et al. Microcirculatory Impairment Is Associated With Multiple Organ Dysfunction Following Traumatic Hemorrhagic Shock: The MICROSHOCK Study. Crit Care Med. 2018 Jun 27. doi: 10.1097/CCM.0000000000003275. [Epub ahead of print]

Naumann DN, Hazeldine J, Bishop J, Midwinter MJ, Harrison P, Nash G et al. Impact of plasma viscosity on microcirculatory flow after traumatic haemorrhagic shock: A prospective observational study. Clin Hemorheol Microcirc. 2018 May 19. doi: 10.3233/CH-180397. [Epub ahead of print]

Forcione M, Colonnese C and Belli A. Cerebral Hemodynamic Influences in Task-Related Functional Magnetic Resonance Imaging and Near-Infrared Spectroscopy in Acute Sport-Related Concussion: A Review. J. Imaging 2018, 4, 59; doi:10.3390/jimaging4040059

Boulton AJ, Lewis CT, Naumann DN, Midwinter MJ. Prehospital haemostatic dressings for trauma: a systematic review. Emerg Med J. 2018 May 4. pii: emermed-2018-207523. doi: 10.1136/emermed-2018-207523. [Epub ahead of print]

Al-Tarrah K, Hewison M, Moiemen N, Lord JM. Vitamin D status and its influence on outcomes following major burn injury and critical illness. Burns Trauma. 2018 Apr 16;6:11. doi: 10.1186/s41038-018-0113-4. eCollection 2018.

Rushton AB, Evans DW, Middlebrook N, Heneghan NR, Small C, Lord J, Patel JM, Falla D. Development of a screening tool to predict the risk of chronic pain and disability following musculoskeletal trauma: protocol for a prospective observational study in the United Kingdom.  BMJ Open. 2018 Apr 28;8(4):e017876. doi: 10.1136/bmjopen-2017-017876

Howroyd F. Supporting the patient innovator. ICU Management & Practice, Volume 18 – Issue 1, Spring 2018

Naumann DN, Hazeldine J, Davies DJ, Bishop J, Midwinter MJ, Belli A et al. Endotheliopathy of trauma is an on-scene phenomenon, and is associated with multiple organ dysfunction syndrome: a prospective observational study. Shock. 2018 Apr;49(4):420-428. doi: 10.1097/SHK.0000000000000999

McWilliams D, Jones C, Atkins G, Hodson J, Whitehouse T, Veenith T, Reeves E, Cooper L, Snelson C. Earlier and enhanced rehabilitation of mechanically ventilated patients in critical care: A feasibility randomised controlled trial. J Crit Care. 2018 Apr;44:407-412. doi: 10.1016/j.jcrc.2018.01.001. Epub 2018 Jan 4

Cato LD, Wearn CM, Bishop JRB, Stone MJ, Harrison P, Moiemen N. Platelet count: a predictor of sepsis and mortality in severe burns? Burns. 2018 Mar;44(2):288-297. doi: 10.1016/j.burns.2017.08.015. Epub 2017 Oct 9

Montague SJ, Delierneux C, Lecut C, Layios N, Dinsdale RJ, Lee CS et al. Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI. Blood Adv. 2018 Feb 13;2(3):240-251. doi: 10.1182/bloodadvances.2017011171.

Calvert M, Kyte D, Mercieca-Bebber R, Slade A, Chan A-W, King M ; and the SPIRIT-PRO Group. Guidelines for Inclusion of Patient-Reported Outcomes in Clinical Trial Protocols: The SPIRIT-PRO Extension. JAMA. 2018 Feb 6;319(5):483-494. doi: 10.1001/jama.2017.21903.

Jain M, Koren S, Miga KH, Quick J, Rand AC, Sasani TA et al. Nanopore sequencing and assembly of a human genome with ultra-long reads.  Nat Biotechnol. 2018;36(4):338-345. doi: 10.1038/nbt.4060. Epub 2018 Jan 29

Naumann DN, Hazeldine J, Midwinter MJ, Hutchings SD, Harrison P. Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding following traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2018;84(1):81-88

Naumann DN, Hancox JM, Raitt J, Smith IM, Crombie N, Doughty H et al. What fluids are given during air ambulance treatment of patients with trauma in the UK, and what might this mean for the future? Results from the RESCUER observational cohort study. BMJ Open Jan 2018, 8 (1) e019627; DOI: 10.1136/bmjopen-2017-019627

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2017

Smith IM, Crombie N, Bishop JR, McLaughlin A, Naumann DN, Herbert M et al. RePHILL: protocol for a randomised controlled trial of pre-hospital blood product resuscitation for trauma. Transfus Med. 2017 Nov 28. doi: 10.1111/tme.12486. [Epub ahead of print]

Naumann DN, Hazeldine J, Dinsdale RJ, Bishop JR, Midwinter MJ, Harrison P, et al. Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study. PLoS One. 2017 Dec 19;12(12):e0189870. doi: 10.1371/journal.pone.0189870. eCollection 2017

Cnossen MC, Huijben JA, van der Jagt M, Volovici V, van Essen T, Polinder S et al. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study. Crit Care. 2017;21(1):233. doi: 10.1186/s13054-017-1816-9.

Roper LS, Nightingale P, Su Z, Mitchell JL, Belli A, Sinclair AJ. Disability from posttraumatic headache is compounded by coexisting posttraumatic stress disorder. J Pain Res. 2017 Aug 21;10:1991-1996. doi: 10.2147/JPR.S129808. eCollection 2017.

Di Pietro V, Lazzarino G, Amorini AM, Signoretti S, Hill LJ, Porto E et al. Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities. Sci Rep. 2017 Aug 23;7(1):9189. doi: 10.1038/s41598-017-09587-2.

Maas AIR, Menon DK, Adelson PD, Andelic N, Bell MJ, Belli A et al. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol. 2017;16(12):987-1048. doi: 10.1016/S1474-4422(17)30371-X. Epub 2017 Nov 6

Lazzarino G, Longo S, Amorini AM, Di Pietro V, D’Urso S, Lazzarino G et al. Single-step preparation of selected biological fluids for the high performance liquid chromatographic analysis of fat-soluble vitamins and antioxidants. J Chromatogr A.2017;1527:43-52. doi: 10.1016/j.chroma.2017.10.053.

Kuravi SJ, Yates CM, Foster M, Harrison P, Hazeldine J, Hampson P et al. Changes in the pattern of plasma extracellular vesicles after severe trauma. PLoS One. 2017;12(8):e0183640. doi: 10.1371/journal.pone.0183640. eCollection 2017

de Cogan F, Hill LJ, Lynch A, Morgan-Warren PJ et al. Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides. Invest Ophthalmol Vis Sci. 2017;58(5):2578-2590. doi: 10.1167/iovs.16-20072

Di Pietro V, Ragusa M, Davies D, Su Z, Hazeldine J, Lazzarino G, et al. MicroRNAs as Novel Biomarkers for the Diagnosis and Prognosis of Mild and Severe Traumatic Brain Injury. J Neurotrauma. 2017 Jun 1;34(11):1948-1956.doi: 10.1089/neu.2016.4857. Epub 2017 Apr 10.

Dinsdale R, Devi A, Hampson P, Wearn C, Bamford A, Hazeldine J, Bishop J, Ahmed S, Watson C, Lord JM, Moiemen N, Harrison P (2017) Changes in novel haematological parameters following thermal injury A prospective observational cohort study. Sci Rep. 2017 Jun 12;7(1):3211. doi: 10.1038/s41598-017-03222-w

Eisenstein N, Naumann DN, Burns DS, Stapley SA, Draper H. Left of Bang Interventions in Trauma: Ethical Implications for Military Medical Prophylaxis. J Med Ethics. 2017 Aug 16. pii: medethics-2017-104299. doi: 10.1136/medethics-2017-104299. [Epub ahead of print]

Hazeldine J, Naumann DN, Toman E, Davies D, Bishop JRB, Su Z, et al. Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study. PLoS Med 14(7): e1002338. https://doi.org/10.1371/journal.pmed.1002338

Faria NR, Quick J, Claro IM, Thézé J, de Jesus JG, Giovanetti M, et al. Establishment and cryptic transmission of Zika virus in Brazil and the Americas. Nature. 2017 Jun 15;546(7658):406-410. doi: 10.1038/nature22401. 

Grubaugh ND, Ladner JT, Kraemer MUG, Dudas G, Tan AL, Gangavarapu K, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. Nature. 2017 Jun 15;546(7658):401-405. doi: 10.1038/nature22400.

Ter Horst B, Chouhan G, Moiemen NS, Grover LM. Advances in keratinocyte delivery in burn wound care. Adv Drug Deliv Rev. 2017 Jun 28. pii: S0169-409X(17)30096-0. doi: 10.1016/j.addr.2017.06.012. [Epub ahead of print]

Tan CL, Alavi SA, Baldeweg SE, Belli A, Carson A, Feeney C et al. The screening and management of pituitary dysfunction following traumatic brain injury in adults: British Neurotrauma Group guidance. J Neurol Neurosurg Psychiatry. 2017;88(11):971-981. doi: 10.1136/jnnp-2016-315500. Epub 2017 Aug 31.

James M. Hancox, Julian Spiers, Nicholas Crombie, and David N. Naumann. Unilateral Dilated Pupil and Spontaneous Cardiac Arrest with Successful Bystander Resuscitation.
Case Rep Emerg Med. 2017;2017:4071531. doi: 10.1155/2017/4071531.

Trzaska WJ, Wrigley HE, Thwaite JE, May RC. Species-specific antifungal activity of blue light. Sci Rep. 2017 Jul 4;7(1):4605. doi: 10.1038/s41598-017-05000-0.

Halstead FD, Webber MA, Oppenheim BA. Use of an engineered honey to eradicate pre-formed biofilms of important wound pathogens: an in vitro study. J Wound Care. 2017;26(8):442-450. doi: 10.12968/jowc.2017.26.8.442

Halstead FD, Kwang Chear Lee, Kwei J, Dretzke J, Oppenheim BA, Moiemen NS. A systematic review of quantitative burn wound microbiology in the management of burns patients. Burns.
Burns. 2017 Aug 4. pii: S0305-4179(17)30360-1. doi: 10.1016/j.burns.2017.06.008. [Epub ahead of print]

Hill LJ, Di Pietro V, Hazeldine J, Davies D, Tomman E, Logan A, Belli A. Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury. Sci Rep. 2017 Jul 10;7(1):5002. doi: 10.1038/s41598-017-04722-5.

Naumann DN, Vincent LE, Pearson N, Beaven A, Smith IM, Smith K, Toman E, Dorrance HR, Porter K, Wade CE, Cotton BA, Holcomb JB, Midwinter MJ. An adapted Clavien-Dindo scoring system in trauma as a clinically meaningful non-mortality endpoint. J Trauma Acute Care Surg. 2017;83(2):241-248. doi: 10.1097/TA.0000000000001517.

Hampson P, Dinsdale RJ, Wearn CM, Bamford A, Bishop J, Hazeldine J, et al. Neutrophil dysfunction, immature granulocytes and NETosis are early biomarkers of sepsis in burn injured patients. Ann Surg. 2017;265(6):1241-1249. doi: 10.1097/SLA.0000000000001807

Dryden MS, Cooke J, Salib RJ, Holding RE, Biggs T, Salamat AA, et al. Reactive oxygen: a novel antimicrobial mechanism for targeting biofilm-associated infection. J Glob Antimicrob Resist.2017;8:186-191

Townsend L, Williams RL, Anuforom O, Berwick MR, Halstead F, Hughes E, et al. Antimicrobial peptide coatings for hydroxyapatite: electrostatic and covalent attachment of antimicrobial peptides to surfaces.J R Soc Interface. 2017 Jan;14(126). DOI: 10.1098/rsif.2016.0657

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, et al. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study. J Neurotrauma. 2017;34(7):1448-1456. doi: 10.1089/neu.2016.4494.

Davies DJ, Clancy M, Lighter D, Balanos GM, Lucas SJ, Dehghani H et al. Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia. J Clin Monit Comput. 2017; 31(5): 967–974.

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2016

Hutchings SD, Naumann DN, Watts S, Wilson C, Burton C, Wendon J, et al. Microcirculatory perfusion shows wide inter-individual variation and is important in determining shock reversal during resuscitation in a porcine experimental model of complex traumatic hemorrhagic shock. Intensive Care Med Exp. 2016;4(1):17. 

Naumann DN, Bowley DM, Midwinter MJ, Walker A, Pallister I. High-Fidelity Simulation Model of Pelvic Hemorrhagic Trauma:The Future for Military Surgical Skills Training? Mil Med. 2016;181, 11/12:1407.

Naumann DN, Mellis C, Husheer SL, Hopkins P, Bishop J, Midwinter MJ, et al. Real-time point of care microcirculatory assessment of shock: design, rationale and application of the point of care microcirculation (POEM) tool. Crit Care. 2016;20(1):310.

Naumann DN, Beaven A, Dretzke J, Hutchings S, Midwinter MJ. Searching for the optimal fluid to restore microcirculatory flow dynamics after haemorrhagic shock: a systematic review of preclinical studies. Shock. 2016;46(6):609-622.

Naumann DN, Smith IM, Beaven A, Midwinter MJ. The term ‘prehospital’ must be justified when reporting animal studies of traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2016; 81(2):394-396.

Eisenstein N, Naumann DN, Bowley DM, Midwinter MJ. Pretrauma Interventions in Force Health Protection: Introducing the “Left of Bang” Paradigm. J Spec Oper Med.2016;16(4)59–63 

Naumann DN, Mellis C, Smith IM, Mamuza J, Skene I, Harris T, et al. Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study. BMJ Open. 2016;6(12): e014162

James M Hancox, Mark J Midwinter, David N Naumann. Show me the evidence! Engaging with science in the pre-hospital environment.
Journal of Paramedic PracticeVol. 8, Iss. 7, 01 Jul 2016, pp 330 – 331

Davies DJ, Clancy M, Lighter D, Balanos GM, Lucas SJ, Dehghani H, Su Z, Forcione M, Belli A. Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia. J Clin Monit Comput. 2016 Oct 24. DOI: 10.1007/s10877-016-9942-5
[Epub ahead of print]

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, et al. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study.J Neurotrauma. 2016 Dec 20. doi: 10.1089/neu.2016.4494

Hutchings SD, Naumann DN, Watts S, Wilson C, Burton C, Wendon J, et al. Microcirculatory perfusion shows wide inter-individual variation and is important in determining shock reversal during resuscitation in a porcine experimental model of complex traumatic hemorrhagic shock. Intensive Care Med Exp. 2016;4(1):17. 

Naumann DN, Bowley DM, Midwinter MJ, Walker A, Pallister I. High-Fidelity Simulation Model of Pelvic Hemorrhagic Trauma:The Future for Military Surgical Skills Training? Mil Med. 2016;181, 11/12:1407.

Naumann DN, Mellis C, Husheer SL, Hopkins P, Bishop J, Midwinter MJ, et al. Real-time point of care microcirculatory assessment of shock: design, rationale and application of the point of care microcirculation (POEM) tool. Crit Care. 2016;20(1):310.

Hazeldine J, Hampson P, Lord JM. The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review. Burns Trauma. 2016;4:33.
DOI 10.1186/s41038-016-0059-3

Naumann DN, Beaven A, Dretzke J, Hutchings S, Midwinter MJ. Searching for the optimal fluid to restore microcirculatory flow dynamics after haemorrhagic shock: a systematic review of preclinical studies. Shock. 2016;46(6):609-622.

Clancy M, Belli A, Davies D, Lucas SJ, Su Z, Dehghani H. Improving the quantitative accuracy of cerebral oxygen saturation in monitoring the injured brain using atlas based Near Infrared Spectroscopy models. J Biophotonics.2016;9(8):812-26.

Davies DJ, Clancy M, Lighter D, Balanos GM, Lucas SJ, Dehghani H, Su Z, Forcione M, Belli A. Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia. J Clin Monit Comput. 2016 Oct 24. DOI: 10.1007/s10877-016-9942-5
[Epub ahead of print]

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, et al. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study.J Neurotrauma. 2016 Dec 20. doi: 10.1089/neu.2016.4494

Naumann DN, Smith IM, Beaven A, Midwinter MJ. The term ‘prehospital’ must be justified when reporting animal studies of traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2016; 81(2):394-396.

Lewis CT,  Naumann DN, Crombie N, Midwinter MJ. Prehospital point-of-care lactate following trauma: A systematic review. J Trauma Acute Care Sur.2016; 81 (4)748–755.

Eisenstein N, Naumann DN, Bowley DM, Midwinter MJ. Pretrauma Interventions in Force Health Protection: Introducing the “Left of Bang” Paradigm. J Spec Oper Med.2016;16(4)59–63 

Naumann DN, Mellis C, Smith IM, Mamuza J, Skene I, Harris T, et al. Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study. BMJ Open. 2016;6(12): e014162

James M Hancox, Mark J Midwinter, David N Naumann. Show me the evidence! Engaging with science in the pre-hospital environment.
Journal of Paramedic PracticeVol. 8, Iss. 7, 01 Jul 2016, pp 330 – 331

Michael Clancy, Antonio Belli, David Davies, Samuel J. E. Lucas, Zhangjie Su, Hamid Dehghani. Improving the quantitative accuracy of cerebral oxygen saturation in monitoring the injured brain using atlas based Near Infrared Spectroscopy models. Journal of Biophotonics. 22 Mar 2016. DOI: 10.1002/jbio.201500302

Hutchings S, Naumann DN, Harris T, Wendon J, Midwinter MJ. Observational study of the effects of traumatic injury, haemorrhagic shock and resuscitation on the microcirculation: a protocol for the MICROSHOCK study. BMJ Open 2016 6:e010893 doi:10.1136/bmjopen-2015-010893

Halstead FD, Webber MA, Rauf M, Burt R, Dryden M, Oppenheim BA. In vitro activity of an engineered honey, medical-grade honeys, and antimicrobial wound dressings against biofilm-producing clinical bacterial isolates. J Wound Care. 2016 Feb; 25(2):93-102. doi: 10.12968/jowc.2016.25.2.93.

Real-time, portable genome sequencing for Ebola surveillanceNature. 2016 Feb 11;530(7589):228-32. doi: 10.1038/nature16996. Epub 2016 Feb 3.Quick J, Loman NJ, Duraffour S, Simpson JT, Severi E, Cowley L, Bore JA, Koundouno R, Dudas G, Mikhail A, Ouédraogo N, Afrough B, Bah A, Baum JH,Becker-Ziaja B, Boettcher JP, Cabeza-Cabrerizo M, Camino-Sánchez Á, Carter LL, Doerrbecker J, Enkirch T, García-Dorival I, Hetzelt N, Hinzmann J, Holm T,Kafetzopoulou LE, Koropogui M, Kosgey A, Kuisma E, Logue CH, Mazzarelli A, Meisel S, Mertens M, Michel J, Ngabo D, Nitzsche K, Pallasch E, Patrono LV,Portmann J, Repits JG, Rickett NY, Sachse A, Singethan K, Vitoriano I, Yemanaberhan RL, Zekeng EG, Racine T, Bello A, Sall AA, Faye O, Faye O,Magassouba N, Williams CV, Amburgey V, Winona L, Davis E, Gerlach J, Washington F, Monteil V, Jourdain M, Bererd M, Camara A, Somlare H, Camara A,Gerard M, Bado G, Baillet B, Delaune D, Nebie KY, Diarra A, Savane Y, Pallawo RB, Gutierrez GJ, Milhano N, Roger I, Williams CJ, Yattara F, Lewandowski K,Taylor J, Rachwal P, Turner DJ, Pollakis G, Hiscox JA, Matthews DA, O’Shea MK, Johnston AM, Wilson D, Hutley E, Smit E, Di Caro A, Wölfel R, Stoecker K,Fleischmann E, Gabriel M, Weller SA, Koivogui L, Diallo B, Keïta S, Rambaut A, Formenty P, Günther S, Carroll MW. Real-time, portable genome sequencing for Ebola surveillance.

 

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2015

Naumann DN, Clarkson A, Midwinter MJ, Crombie N. Prehospital rapid sequence induction following trauma in the era of regional networks for major trauma. Eur J Emerg Med. 2015. doi: 10.1097/MEJ.0000000000000364.

Smith IM, Naumann DN, Guyver P, Bishop J, Davies S, Lundy JB and Bowley DM. Inter-observer variability in injury severity scoring after combat trauma: different perspectives, different values? Journal of Special Operations Medicine. 2015;15(2):86-93.

Naumann DN, Dretizke J, Hutchings S, Midwinter MJ. Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models. 2015 Aug. Available online at http://www.dcn.ed.ac.uk/camarades/research.html#protocols

Smith IM, Naumann DN, Marsden MER, Ballard M and Bowley DM. Scanning and War: Utility of FAST and CT in the assessment of battlefield abdominal trauma. Annals of Surgery. 2015 Aug;262(2):389-96. Epub ahead of print.

Toman E, Harrisson S, Belli T. Biomarkers in traumatic brain injury: a review. J R Army Med Corps. 2015 Nov 2. pii: jramc-2015-000517. doi: 10.1136/jramc-2015-000517.

Toman E, Beaven A, Balogun M, Porter K. Ovarian vein thrombosis in a polytrauma patient. BMJ Case Rep. 2015 Dec 18;2015. pii: bcr2015213071. doi: 10.1136/bcr-2015-213071.

Naumann DN, Clarkson A, Midwinter MJ, Crombie N. Prehospital rapid sequence induction following trauma in the era of regional networks for major trauma. Eur J Emerg Med. 2015. doi: 10.1097/MEJ.0000000000000364.

Jansen JO, Morrison JJ, Tai NRM, Midwinter MJ. A survey of major trauma centre staffing in England. J R Army Med Corps2015;161:341–344. doi:10.1136/jramc-2014-000350.

Hazeldine J, Lord JM, Belli A. Traumatic brain injury and peripheral immune suppression: primer and prospectus. Front. Neurol. 2015 Nov 05. 6:235. doi: 10.3389/fneur.2015.00235.

Hazeldine J, Lord JM, Hampson P. Immunesenescence and inflammaging: A contributory factor in the poor outcome of the geriatric trauma patient. Ageing Res Rev. 2015 Oct 17. pii: S1568-1637(15)30028-3. doi: 10.1016/j.arr.2015.10.003. Epub ahead of print.

Niebel M, Quick J, Prieto AM, Hill RL, Pike R, Huber D, David M, Hornsey M, Wareham D, Oppenheim B, Woodford N, van Shaik W, Loman N. Deletions in a ribosomal protein-coding gene are associated with tigecycline resistance in Enterococcus faecium. 2015 Aug. Epub ahead of print.

 

Smith IM, Naumann DN, Guyver P, Bishop J, Davies S, Lundy JB and Bowley DM. Inter-observer variability in injury severity scoring after combat trauma: different perspectives, different values? Journal of Special Operations Medicine. 2015;15(2):86-93.

Halstead FD, Rauf M, Moiemen NS, Bamford A, Wearn CM, Fraise AP, Lund PA, Oppenheim BA, Webber MA. The antibacterial activity of acetic acid against biofilm-producing pathogens of relevance to burns patients. PLoS One. 2015 Sep. Epub.

Kelly M, Williams R, Aojula A,  O’Neill J, Trzincska Z, Grover LM, Scott RA, Peacock AF,  Logan A, Stamboulis A, de Cogan F. Peptide Aptamers: Novel Coatings for Orthopaedic Implants. Materials Science and Engineering C. 2015 Sep;54:84-93.

Naumann DN, Dretizke J, Hutchings S, Midwinter MJ. Protocol for a systematic review of the impact of resuscitation fluids on the microcirculation after haemorrhagic shock in animal models. 2015 Aug. Available online at http://www.dcn.ed.ac.uk/camarades/research.html#protocols

Hammond D, Davies DJ, Su Z. Do we forget to treat concussion? Faculty Dental Journal. 2015. http://dx.doi.org/10.1308/204268515X14174408396046

Smith IM, Naumann DN, Marsden MER, Ballard M and Bowley DM. Scanning and War: Utility of FAST and CT in the assessment of battlefield abdominal trauma. Annals of Surgery. 2015 Aug;262(2):389-96. Epub ahead of print.

Halstead FD, Rauf M, Moiemen NS, Bamford A, Wearn CM, Fraise AP, Oppenheim BA, Webber MA. Antimicrobial dressings: Comparison of the ability of a panel of dressings to prevent biofilm formation by key burn wound pathogens. Burns. 2015 Jul. Epub ahead of print.

Hazeldine J, Hampson P, Adeusi Opoku F, Foster M and Lord JM. N-formyl peptides drive mitochondrial damage associated molecular pattern induced neutrophil activation through ERK1/2 and P38 MAP Kinase signalling pathways. Injury. 2015 Jun;46(6):975-84.

Erika Check Hayden. Pint-sized DNA sequencer impresses first users. Nature. 2015 May;521:15–16.

Penn-Barwell JG, Roberts SAG, Bishop JRB, Midwinter MJ. Improved survival in UK combat casualties from Iraq and Afghanistan: 2003-2012. J Trauma Acute Care Surg. 2015:78(5);1-7.

Alshehri OM, Montague S, Watson S, Carter P, Sarker N, Manne BK, Miller JL, Herr AB, Pollitt AY, O’Callaghan CA, Kunapuli SP, Arman M, Hughes CE, Watson SP. Activation of Glycoprotein VI (GPVI) and C-type Lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochem J. 2015 Apr; Epub ahead of print.

Smith IM, Beech ZK, Lundy JB and Bowley DM. A prospective observational study of abdominal injury management in contemporary military operations: Damage control laparotomy is associated with high survivability and low rates of fecal diversion. Annals of Surgery. 2015 Apr;261(4):765-73. Epub ahead of print.

Davies D et al. Near Infrared Cerebral Spectroscopy in the monitoring of adult patients with traumatic brain injury: A review of the current literature. J. Neurotrauma. 2015 Apr; Epub ahead of print.

Chaudhary R, Upendran M, Campion N, Yeung A, Blanch R, Morgan-Warren P, Gibb I, Nelson T and Scott R. The role of computerised tomography in predicting visual outcome in ocular trauma patients. Eye. 2015 Apr; Epub ahead of print.

Penn-Barwell JG, Peleki A, Chen YF, Bishop JRB, Midwinter MJ, Rickard RF. Intraoperative fluid irrigation for traumatic wounds (Protocol). Cochrane Review (protocol). Available online at http://www.cochrane.org/CD011555/WOUNDS_intraoperative-fluid-irrigation-for-traumatic-wounds

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2014

Hazeldine J, Hampson P, Lord JM. The impact of trauma on neutrophil function. Injury, 2014.

Su Z, Davies DJ, et al. Self-reported outcomes after head injury – assault as a red flag for adverse outcomes. European Journal of Trauma and Emergency Surgery. 2014, 40 (Suppl 1):S12

Davies DJ, Su Z, et al. Traumatic brain injury – can the initial Marshall grading of CT scan be useful in predicting self-reported outcomes after survival? British Journal of Neurosurgery. 2014, 28(2): 168.

Westwood J, Burnett M, Spratt D, et al.  The hospital microbiome project: meeting report for the UK science and innovation network UKUSA workshop ‘beating the superbugs: hospital microbiome studies for tackling antimicrobial resistance’. Standards in Genomic Sciences 2014. 2013 Oct;9:12

Salter S, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, Turner P, Parkhill J, Loman N, Walker AW. Reagent contamination can critically impact sequence-based microbiome analyses. BMC Biol. 2014 Nov;12:87

Halachev MR, Chan JZ, Constantinidou CI, Cumley N, Bradley C, Smith-Banks M, Oppenheim B, Pallen MJ. (2014). Genomic Epidemiology of a Protracted Hospital Outbreak caused by Multi-Drug-Resistant Acinetobacter baumannii in Birmingham, England. Genome Med. 2014 Nov;6(11):70

Quick J, Cumley N, Wearn CM, Niebel M, Constantinidou C, Thomas CM, Pallen MJ, Moiemen NS, Bamford A, Oppenheim B, Loman NJ. Seeking the source of Pseudomonas aeruginosa infections in a recently opened hospital: a role for whole-genome sequencing. BMJ Open. 2014 Nov;4(11)

Alneberg J, Bjarnason BS,  de Bruijn I, Schirmer M,  Quick J,  Ijaz UZ, Lahti L,  Loman NJ, Andersson AF & Quince C . Binning metagenomic contigs by coverage and composition. Nature Methods. 2014, 11: 1144–1146

Mendoza L, Vilela R, Voelz K, Ibrahim AS, Voigt K, Lee SC. Human fungal pathogens of mucorales and entomophthorales. Cold Spring Harb Perspect Med. 2014

Voelz K, Johnston SA, Smith LM, Hall RA, May RC. “Division of Labour” in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak. Nat Commun. 2014 Oct 17;5:5194

Quick J, Quinlan AR, Loman NJ. A reference bacterial genome dataset generated on the MiniION portable single molecule nanopore sequencer. Gigascience. 2014 Oct 20;3:22

Dretzke J, Smith IM, James R, Midwinter MJ. Protocol for a systematic review of the clinical effectiveness of pre-hospital blood components compared to other resuscitative fluids in patients with major traumatic haemorrhage. Syst Rev. 2014 Oct 24, 3(1):123

Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P, Lilford RJ. The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet. 2014. 384:1455-1465

El Ghoul W, HarrissonS, Belli A. (2014). Autologous cranioplasty following decompressive craniectomy in the trauma setting. British journal of neurosurgery. 2014 Oct;0:1-6

Aisling Clarkson. Trauma Research – Delivering in an Emergency Setting. Faculty World eMagazine. Sept 2014 issue

O’Reilly DJ, Morrison JJ, Jansen JO, Nordmann G, Rasmussen TE, Midwinter MJ, Doughty H. Initial UK experience of prehospital blood transfusion in combat casualties. J Trauma Acute Care Surg. 2014, 77: S66 – S70

O’Reilly DJ, Morrison JJ, Jansen JO, Apodaca AN, Rasmussen TE, Midwinter MJ. Prehospital blood transfusion in the en route management of severe combat trauma: A matched cohort study. J Trauma Acute Care Surg. 2014;77:S114–S120

Sabiiti W, Robertson E, Beale MA, Johnston SA, Brouwer AE, Loyse A, Jarvis JN, Gilbert AS, Fisher MC, Harrison TS, May RC, Bicanic T. Efficient phagocytosis and laccase activity affect the outcome of HIV-associated cryptococcosis. J. Clin Investigation 2014;124(5):2000

Quick J, Constantinidou C, Pallen MJ, Oppenheim B, Loman NJ. Draft Genome Sequence of Elizabethkingia meningoseptica Isolated from a Traumatic Wound. Genome Announc. 2014 May 8;2(3)

Bulstrode H, Nicoll JA, Hudson G, Chinnery PF, Di Pietro V, Belli A. Mitochondrial DNA and traumatic brain injuryAnnals of neurology. 2014; 75(2): 186-195

Morrison JJ, Stannard A, Midwinter MJ, Sharon DJ, Eliason JL, Rasmussen TE. Prospective evaluation of the correlation between torso height and aortic anatomy in respect of a fluoroscopy free aortic balloon occlusion system. Surgery. 2014 Jun;155(6):1044-51. doi: 10.1016/j.surg.2013.12.036. Epub 2014 Jan.

Fries CA, Ayalew Y, Penn-Barwell JG, Porter K, Jeffery SL, Midwinter MJ. Prospective randomised controlled trial of nanocrystalline silver dressing versus plain gauze as the initial post-debridement management of military wounds on wound microbiology and healing. Injury. 2014 Jul;45(7):1111-6. doi: 10.1016/j.injury.2013.12.005. Epub 2013 Dec.

Kolias AG, Bulters DO, Cowie CJ, et al. British Neurosurgical Trainee Research Collaborative; British Neurotrauma Group; UKCRR Collaborative Group. Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR). Br J Neurosurg. 2014 Jun;28(3):310-4. doi: 10.3109/02688697.2013.859657

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2013

Voelz K, Ma H, Phadke S, Byrnes EJ, Zhu P, et al. Transmission of Hypervirulence traits via sexual reproduction within and between lineages of the human fungal pathogen cryptococcus gattii. PLoS Genet. 2013;9(9):e1003771. doi: 10.1371/journal.pgen.1003771. Epub 2013 Sep 5

Blanch RJ, Good PA, Shah P, Bishop JR, Logan A, Scott RA. Visual outcomes after blunt ocular trauma. Ophthamol. 2013;120:1588 -91

Mendelow AD, Gregson BA, Rowan EN, Murray GD, Gholkar A, Mitchell PM; STICH II Investigators. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial. Lancet. 2013 Aug 3;382(9890):397-408. doi: 10.1016/S0140-6736(13)60986-1. Erratum in: Lancet. 2013 Aug 3;382(9890):396

Fraise AP, Wilkinson MA, Bradley CR, Oppenheim B, Moiemen N. The antibacterial activity and stability of acetic acid. J.  Hosp. Infect. 2013;84(4):329–31

Scott R. The Eye in War. Internat Rev Armed Forces Med Services. 2013;86:17-24

Vagnozzi R, Signoretti S, Floris R, et al. Decrease in N-acetylaspartate following concussion may be coupled to decrease in creatine. J Head Trauma Rehabil. 2013 July-Aug;28(4):284-92

Kolias AG, Scotton WJ, Belli A, et al. UK Neurosurgical Research Network; RESCUE-ASDH collaborative group. Surgical management of acute subdural haematomas: current practice patterns in the United Kingdom and the Republic of Ireland. Br J Neurosurg. 2013 Jun;27(3):330-3

Jansen JO, Lord JM, Thickett DR, Midwinter MJ, McAuley DF, Gao F. Clinical review: Statins and trauma–a systematic review. Crit Care. 2013 May 29;17(3):227. doi: 10.1186/cc12499

Zaben M, El Ghoul W, Belli A. Post-traumatic head injury pituitary dysfunction. Disabil Rehabil. 2013 Mar;35(6):522-5

Penn-Barwell JG, Bennett PM, Fries CA, Kendrew JM, Midwinter MJ, Rickard RF. Severe open tibia fractures in combat trauma: management and preliminary outcomes. Bone Joint J. 2013 Jan;95-B(1):101-5

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2012

Chan JZ, Halachev MR, Loman NJ, Constantinidou C, Pallen MJ. Defining bacterial species in the genomic era: insights from the genus Acinetobacter. BMC Microbiol. 2012 Dec;12:302

Chan JZ, Pallen MJ, Oppenheim B, Constantinidou C. Genome sequencing in clinical microbiology. Nat Biotechnol. 2012 Nov;30(11):1068-71

Morrison JJ, Ross JD,Dubose JJ, Jansen JO, Midwinter MJ & Rasmussen TE. Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury. Arch Surg. 2012;E2-E8