Dex-CSDH

Full title: A randomised, double blind, placebo-controlled trial of a two-week course of dexamethasone for adult patients with a symptomatic Chronic Subdural Haematoma

Aim: assess the potential benefits of the cortico-steroid dexamethasone on chronic subdural haematomas

Background: a chronic subdural haematoma is a collection of blood between the surface of the brain and its outermost lining. It is especially common in older people and can happen with only a minor injury. Patients with severe symptoms usually undergo an operation to remove the blood collection. Approximately 80% of patients do well following this operation, however in a minority of cases a further operation is required, due to a recurrence. There is evidence to show that steroids could reduce the rate of recurrence and, in some cases, may avoid the need for surgery altogether. We wish to assess the potential benefits of the cortico-steroid dexamethasone. This drug is a licensed medication in regular use, but is not currently licensed for the treatment of subdural haematomas.