The cross-cutting PROMs theme provides expert methodological input to ensure that patient-reported outcomes are appropriately incorporated into trauma trials and broader research to ensure rigorous collection of outcomes that matter to trauma patients such as impact of treatment on patient symptoms and quality of life.

In addition, this theme is leading a project to develop and test the usability and acceptability of an electronic Patient Reported Outcome Measure (ePROM) platform for use with patients who have experienced a traumatic brain injury (TBI).

The Diagnostic, Drug, Devices and Biomarkers (D³B) trial management team is part of the CRUK clinical trials unit based within the University of Birmingham https://www.birmingham.ac.uk/research/activity/mds/trials/crctu/index.aspx

D³B are responsible for providing support to Clinical investigators/research intuitions and industry in all aspects of medical research within the NHS including; Grant and funding application, collaboration with industry partners, Trial methodology, Study design, Regulatory submission, Trial Management, Data Analysis and publication. In addition, the team supports all aspects of drug development, medical device development and supports investigators in their discussion with national and international regulatory agencies, industry and other academic partners.

In the SRMRC, D³B work on:

• ACETICA – A pilot randomised controlled trial to examine the efficacy and optimal dose of Acetic Acid to treat colonised burns wounds
• ADAPT – A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone and its Profile in Trauma